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Title Chemistry and pharmacology of anticancer drugs / David E. ThurstonBooks
Name(s) Thurston, David E. (Main Author)
Publication Boca Raton : CRC Press, c2007
Physical Details 290 p.; ill.; 25 cm.
Subjects Antineoplastic agents
ISBN 0849392195 (hc.)
9780849392191 (hc.)
Classmarks 616.994061
Notes Bib. & Index: Includes bibliographical references and index.
Contents: Forward. -- Acknowledgements. -- Dedication. -- Biography of Author. -- 1. Introduction to Cancer. -- 2. Antimetabolites. -- 3. DNA-Interactive Agents. -- 4. Antitubulin Agents. -- 5. Cell Signaling Inhibitors. -- 6. Hormonal Therapies. -- 7. Tumour Targeting Strategies. -- 8. Biologicals. -- 9. The Future. -- 10. Personalized Medicine (Oncogenomics). -- 11. Adjunct Therapies. -- Index.
Summary: "After reviewing the causes of cancer and the philosophy of drug discovery, Chemistry and Pharmacology of Anticancer Drugs surveys those clinically relevant families of anticancer agents (including biological agents) in use, as well as those currently being researched. The author discusses the history of each agent, and offers a detailed discussion of its chemistry, mechanism of action, spectrum of activity, side effects, and formulation issues in the context of structure and chemistry. Uniquely, this work details the full chemical structures of the agents, and when possible includes both generic and trade names. It also introduces new research tools and methodologies."--Publisher's description.
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00439458Science and Agriculture LibraryS616.994061:T544c:c.1AvailableStandard Loan
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